COVID-19 Spike Protein Impairs DNA Repair and Can Be Reverse Transcribed into Human DNA According to Two Studies
Two studies which show the COVID-19 spike protein which is also encoded in the mRNA of COVID-19 vaccines, impairs DNA repair, and can be reverse transcribed into human DNA.
Several studies have been published now showing irrefutable evidence, that the COVID-19 spike protein which is also encoded in the mRNA of COVID 19 Vaccines a) can be reverse transcribed into Human DNA, and b) Impairs DNA repair mechanisms, further compounding the ill health effects. This is no longer a “conspiracy”, this is fact evidenced by several studies. Therefore the question isn’t “Does the spike protein in COVID-19 mRNA vaccines effect DNA?”…the questions instead becomes “how severe is the damage” and “What are the possible consequences of permanently altering the human genome?
“Our study is the first in vitro study on the effect of Covid-19 mRNA vaccine BNT162b2 on human liver cell line. We present evidence on fast entry of BNT162b2 into the cells and subsequent intracellular reverse transcription of BNT162b2 mRNA into DNA.”Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
In another article on COVID-19 vaccines and blood clots, we analyzed multiple studies which proved undeniably that a) The Spike Protein independently is a dangerous toxin, which causes many of the symptoms associated with COVID-19 and b) the mRNA and spike protein travel past the injection site and proliferate throughout the body; contrary to assertions made by big pharma and vaccine manufacturers that the mRNA stays at the injection site, and that the spike protein produced by the mRNA injected instructions, is harmless without the virus. What this could mean in light of this new information on DNA inhibition and reverse transcription, does not bode well for the health of COVID-19 vaccinated individuals.
- Spike Protein Enters Cell Nuclei and Impairs DNA Repair
- Natural News Article on Swedish Study – Explains DNA Repair Mechanism(s) and Importance
- HighWire on Swedish Study and How Spike Protein Damages DNA | Video
- Dr. Mobeen Syed Analysis of Study
- What Does it Mean if DNA Repair Mechanisms are Inhibited by the Spike Protein?
- More About the BRCA1 Gene
- The effect of BRCA1 on Ovarian Supply and Female Fertility
- Spike Protein Reverse Transcription into Human DNA
- What is mRNA and How Does Reverse Transcription Work?
Spike Protein Enters Cell Nuclei and Impairs DNA Repair
In a study published in Oct 2021 titled SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro, authored by Hui Jiang and Ya-Fang Mei, researchers found that the Spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment:
“Here, by using an in vitro cell line, we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity. Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.“SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
DNA damage occurs daily throughout the body…however through these and other mechanisms that damage is quickly repaired. However this study reveals the spike protein is capable of crippling your bodies ability to repair that DNA damage. If your body’s ability to repair DNA damage is inhibited, things which are normally harmless, such as the various radiations we are exposed to daily, or even potential damage by vaccine ingredients, become a catalysts for permanent DNA damage and diseases such as cancer or auto immune disorders.
Scientists have known for some time now that the spike protein travels past the injection site and is independently responsible for much of the damage caused by COVID-19, contrary to what the vaccine manufacturers told us early on… which makes the fact that it can inhibit DNA repair even more alarming.
Please Note: Some individuals who support experimental mRNA drug injections, will highlight how this study (and others) is referring to the spike protein present in the COVID-19 virus and not the spike protein generated by your cells as instructed by the mRNA in COVID-19 vaccines. And because the mRNA Spike Protein is only around 50-60% similar to the natural version (missing proteins, etc)…that this study can’t possibly be relevant in pointing out the dangers of COVID-19 vaccines; they therefore labeled this article as misinformation. What these individuals don’t have is any evidence or peer reviewed in-vivo (in body) studies, to show these differences in the mRNA vs natural spike protein correlate to a reduction in the negative health impacts caused by the mRNA generated spike protein, nor to what degree these differences translate to reduced health risks – they are essentially putting forth a hypothesis to discredit a study…this has been used on reddit and other social media platforms to censor this article and have me permanently banned. In fact the evidence is available to show that the COVID-19 mRNA Spike Protein is very capable of negatively impacting multiple organs, and causing mass illness in the unprecedented rise of COVID-19 vaccine injuries, and the fact that COVID-19 vaccines have now caused 23X more deaths than all other vaccines combined in the last 20 years.
Natural News Article on Swedish Study – Explains DNA Repair Mechanism(s) and Importance
In an article by Planet today (republished from a Natural News Article), they break down the Swedish study: explain in simple terms how DNA repair mechanisms function and why these operations are very necessary to prevent illness.
“This means that the spike protein, which is generated in cell ribosomes after the cells have been hijacked by mRNA vaccines, doesn’t always leave the cell and enter the bloodstream as we are told by mRNA vaccine proponents. In some cases, the spike protein enters the cell nucleus. There, it interferes with the DNA repair mechanism as described throughout this article.
This means, without question, mRNA vaccines result in chromosomal alterations in the body’s cells. It is confirmation that such vaccines are, indeed, wreaking havoc with genetic integrity and are exhibiting side effects that have not been anticipated or described by mRNA vaccine proponents”Article by Planet today (republished from a Natural News Article)
Here is an excerpt from the article where they explain the suppression of NHEJ repair:
Full-length spike protein resulted in the greatest suppression of NHEJ DNA repair mechanism
See the figures below. SARS-CoV-2 viral fragments are named “Nsp1, Nsp5” and so on. The full-length spike is referred to as “Spike” and the nucleocapsid — another structural part of the whole spike protein pathogen — is identified separately.
Figures C and E show the suppression of NHEJ repair by these various portions of viral fragments. (See the blue vertical graph lines representing activity / efficiency levels of the DNA repair mechanism).
This data shows that the greatest suppression of NHEJ activity is measured when the full spike protein is present. This is the spike protein which is generated by the body’s own cells after being injected with an mRNA vaccine:
In figure 2, below, we see that the suppression of NHEJ activity exhibits a dose-dependent response to the presence of spike protein (figures 2B and 2C). This indicates that the more spike proteins are present, the greater the suppression of DNA repair:
The bottom right figure, 2G, shows how the presence of the spike protein inhibits DNA repair, following various insults to the DNA including but not limited to: radiation, chemical exposure or oxidation. Importantly, as the study authors explain:
“Following different DNA damage treatments, such as ?–irradiation, doxorubicin treatment, and H2O2 treatment, there is less repair in the presence of the spike protein (Figure 2F,G). Together, these data demonstrate that the spike protein directly affects DNA repair in the nucleus.”SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
The DNA repair mechanism, known as NHEJ (Non-Homologous End Joining) is a kind of intracellular “emergency response” system that repairs double-stranded DNA breaks. Without the NHEJ mechanism, all advanced multi-cellular life would cease to exist. No human being, animal or plant can survive with the integrity of its genetic code being protected and constantly repaired through multiple mechanisms.
In a normal, healthy person, the NHEJ mechanism repairs the DNA and prevents a bad mutation from occurring. But in the presence of the vaccine spike protein, NHEJ effectiveness is suppressed by as much as 90%, meaning it is unable to do its job due to the suppressed ability to recruit proteins for repair.
HighWire on Swedish Study and How Spike Protein Damages DNA | Video
Dr. Mobeen Syed Analysis of Study
What Does it Mean if DNA Repair Mechanisms are Inhibited by the Spike Protein?
If what these studies say relevant and valid…then those who have been injected with these COVID-19 mRNA and adenovirus vectored injections, have crippled their ability to repair DNA damage…giving normally harmless radiation the capability to cause severe biological DNA damage, and become something life threatening, which can cause genetic mutations and a plethora of diseases, including cancer and auto immune disorders.
DNA damage can be caused by exposure to radiation, chemicals found in foods and personal care products, or even exposure to mammography equipment. Excessive sunlight exposure can also cause DNA breaks, and minor DNA mutations occur spontaneously in all living organisms. Airline pilots, for example, are routinely exposed to ionizing radiation due to flying at altitude. Sources of radiation include:
- Sunlight – UVA and UVB solar radiation
- EMF Radiation (Electromagnetic Fields) Includes radiation from things like: routers, smartphones, laptops smart meters, hotspots, smart tvs, gaming consoles, wireless cameras or printers, etc
- 5G Radiation – 5G exposure results in peroxynitrite production in the blood an extremely dangerous free radical that causes DNA damage in brain cells and tissue cells across the body.
- 2.5G & 4G or WiFi Radiation – Includes routers, hot spots, and cell towers
- Chemicals or carcinogens in food, cleaners or personal care products such: laundry detergents, perfumes, shampoos, skin lotions, etc
DNA Repair inhibition can permit the following “errors” be introduced into chromosomes inside the nuclei of human cells, which includes:
- Mutations or “errors” in the genetic sequence.
- DELETIONS of entire segments of genetic code.
- INSERTIONS of incorrect segments.
- Mixing and matching / permutations of genetic code.
These errors, when expressed through cell division and replication, can result in:
- An explosion in cancer and cancer tumors throughout the body
- Loss of production of immune system B and T cells (i.e. induced immunodeficiency)
- Autoimmune disorders
- Accelerated aging and reduced telomere length
- Loss of functioning of complex organ systems such as circulatory, neurological, endocrine, musculoskeletal, etc.
- Cellular damage resembling radiation poisoning as cells destroy themselves from within
Spike Protein’s Suppression of NHEJ DNA Repair Mechanism Can Cause Reduced Lifespan and Accelerated Aging
In addition DNA damage repair, especially NHEJ repair, is essential for V(D)J recombination, which lies at the core of B and T cell immunity. As Science Direct also explains: Maintaining genomic integrity is imperative for the survival of an organism. Among different DNA damages, double-strand breaks (DSBs) are considered as most deleterious since they can lead to cell death if left unrepaired or chromosomal rearrangements when mis-repaired, leading to cancer.
Further, mutations in NHEJ genes including Ku70 and Ku80 have been associated with shortened life spans in mice . In addition, defects in DNA-PKcs (DNA-dependent protein kinase) resulted in impaired telomere maintenance and shortened life span in mice . Taken together, these lines of evidence suggest that NHEJ plays an important role in preventing age-related increase in genomic instability and functional decline. In effect, this means the spike protein’s suppression of the NHEJ DNA repair mechanism also leads to reduced lifespan and accelerated aging.
More About the BRCA1 Gene
“This gene encodes a 190 kD nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The BRCA1 gene contains 22 exons spanning about 110 kb of DNA. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2020]”GeneCards.Org
The effect of BRCA1 on Ovarian Supply and Female Fertility
An NIH study in 2013 titled A molecular explanation for age-related fertility decline in women, researchers suggested that if woman’s oocytes contain mutant versions of BRCA1, she can exhaust her ovarian supply sooner:
The research team’s findings stemmed from their initial focus on BRCA1, a DNA repair gene that has been closely studied for nearly 20 years because defective versions of it dramatically increase a woman’s risk of breast cancer.
“Using mice bred to lack the BRCA1 gene, the NICHD-supported scientists confirmed that a healthy version of BRCA1 is vital to reproductive health. BRCA1-deficient mice were less fertile, had fewer oocytes, and had more double-stranded DNA breaks in their remaining oocytes than did normal mice.
Abnormal BRCA1 appears to cause the same problems in humans—the team’s studies suggest that if a woman’s oocytes contain mutant versions of BRCA1, she will exhaust her ovarian supply sooner than women whose oocytes carry the healthy version of BRCA1.
Together, these findings show that the ability of oocytes to repair double-stranded DNA breaks is closely linked with ovarian aging and, by extension, a woman’s fertility. This molecular-level understanding points to new reproductive therapies. Specifically, the scientists suggest that finding ways to bolster DNA repair systems in the ovaries might lead to treatments that can improve or prolong fertility.”A molecular explanation for age-related fertility decline in women
Spike Protein Reverse Transcription into Human DNA
In a study published in Feb of 2022 titled Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line, Researchers showed that BNT162B2 mRNA is “reverse transcribed intracellularly into DNA”:
“Our results indicate a fast up-take of BNT162b2 into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure.”Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
You can read over the Abstract which also goes into a bit of detail on how they analyzed the Huh7 cells, in order to discover LINE-1 changes and reverse transcription of BNT162b2 into DNA; using “PCR on genomic DNA of Huh7 cells exposed to BNT162b2”:
“Huh7 cells were exposed to BNT162b2, and quantitative PCR was performed on RNA extracted from the cells. We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase. Immunohistochemistry using antibody binding to LINE-1 open reading frame-1 RNA-binding protein (ORFp1) on Huh7 cells treated with BNT162b2 indicated increased nucleus distribution of LINE-1. PCR on genomic DNA of Huh7 cells exposed to BNT162b2 amplified the DNA sequence unique to BNT162b2″Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
Dr. Jessica rose explains in a bit more detail what HUH cells are and what LINE-1 is:
“Huh cells are ‘immortal’ liver tumor cells and grow ad-infinitum if you give them love…LINE-1 is a reverse transcriptase that we carry and comprises ~17% of our genome!”Jessica Rose
If you didn’t quite grasp what they are saying in the abstract, further into the study they explain it in in simpler terms…that a possible mechanism for the reverse transcription of the Spike protein is through “endogenous [intracellular] reverse transcriptase LINE-1, the distribution of which is elevated by BNT162B2”:
“A possible mechanism for reverse transcription is through endogenous [intracellular] reverse transcriptase LINE-1, and the nucleus protein distribution of LINE-1 is elevated by BNT162b2,”Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
So you should be able to piece together here what the study is saying…LINE-1 is a “reverse transcriptase”, which comprises “17% of our genome” and decreases with age. The COVID-19 mRNA (BNT162B2) is able to enter human liver cell line (Huh7), and in as quickly as 6 hrs post-injection, is able to reverse transcribe into human DNA.
Dr. Peter McCullough on Study
“That means DNA is made from the Pfizer mRNA code, and that is installed into the human genome…the CDC has always said don’t worry! These vaccines don’t alter human DNA. This is the first paper to show that at least, the middle 444 base pair clearly is in human DNA”Dr. Peter McCullough in Video Analysis of Study: Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
Dr. Mobeen Syed Study Analysis
Dr. Mobeen Syed has been covering studies and information regarding COVID-19 and COVID-19 vaccines throughout the pandemic…In the video below, Dr. Mobeen Syed, host of Dr. Been, explains this study in layman’s terms (Starting at timestamp 8:17):
What Does it Mean if BNT162B2 Can be Reverse Transcribed into Human DNA?
It’s important you understand the significance of what this means…once something is transcribed into your human DNA, it is present in every cell in your body and is therefore virtually impossible to remove. In other words if the spike protein (and possibly other genes) are in fact being reverse transcribed into the human genome, it is permanent, and if the vaccinated manage to have children, the DNA can and will persist in offspring.
“Our study shows that [Pfizer’s mRNA injection] … can be reverse transcribed to DNA … and this may give rise to the concern if [injection]-derived DNA may be integrated into the host genome and affect the integrity of genomic DNA, which may potentially mediate genotoxic side effects.”Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
Even more concerning is that we also know the S-Protein inhibits DNA repair…which could further enhance reverse transcription of the S-protein by negating your bodies ability to prevent it…therefore worsening the irreparable damage caused by these COVID-19 vaccines, to the human genome.
Reverse Transcribes into Human DNA Can Retard Embryogenesis | Special Mention
In an article by Jessica Rose she covers the above study, and mentions the potential for the Reverse transcribes into human DNA, to negatively impact successful embryogenesis via effects on LINE-1 expression:
“…LINE-1 is a reverse transcriptase that we carry and comprises ~17% of our genome! LINE-1 retrotransposons are necessarily active during embryogenesis are aberrantly active in tumorigenesis.
As can be seen in the following figure extracted from the paper (Figure 3), they found significantly increased LINE-1 expression (V3 = 2.0 µg/mL BNT162b2) compared to control and decreased LINE-1 expression (V1 and V2 = lower BNT162b2 concentrations) at all time points measured.
LINE-1 retrotransposons are also involved during early embryonic development. Since LINE-1 expression levels are significantly increased then what effect is this over-expression having on embryogenesis?”
“We found that too much or too little LINE-1 expression caused development to come to a halt. This means that the precise timing and level of retrotransposon expression is critical for the development of the embryo.”Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
These concerns regarding effects on embryonic development are verified in VAERS data from early this year:
What is mRNA and How Does Reverse Transcription Work?
What is Reverse Transcriptase – An HIV Life Cycle Example | Video
This video explains “reverse transcriptase” with HIV as an example:
“We made a big mistake. We didn’t realize it until now…We thought the spike protein was a great target antigen, we never knew the spike protein itself was a toxin and was a pathogenic protein. So by vaccinating people we are inadvertently inoculating them with a toxin.”Byram Bridle, a viral immunologist and associate professor at University of Guelph, Ontario in an article by Children’s Health Defense
We now have through several studies established the following facts:
- The Spike Protein independently is a dangerous toxin, which causes many of the symptoms associated with COVID-19
- The mRNA and spike protein travel past the injection site and proliferate throughout the body and can persist for months post-injection (Source: https://pubmed.ncbi.nlm.nih.gov/35148837/)
- Spike can be found up to 15 months later in monocytes and other cells (Source: https://pubmed.ncbi.nlm.nih.gov/35082777/)
- The Spike Protein impairs DNA Repair (study cited above)
- The Spike Protein can be reverse transcribed into the human genome (DNA) (study cited above)
The questions we must now ask are:
- How detrimental will the DNA damage and subsequent negative health effects be?
- Does the body have any way of recovering from this damage?
- Will modern medicine find a way to mitigate or even cure some of the ill health effects caused by these experimental COVID-19 injections?
- What does this mean for the integrity of the human genome, and the survival of the human species?
I hypothesize what we are already seeing, including a massive increase in severe COVID-19 infection among the vaccinated, as well as various cancers and auto-immune disorders will only worsen…until they progress into a global health epidemic, which governments around the world will capitalize on to further tighten the shackles around their enslaved citizens, and usher in the great reset they seem so fond of.
The colossal failure of the COVID-19 mRNA vaccines, and the new data released monthly of adverse events… is a perfect example of why vaccine development usually takes 10-15+ years, and is tested extensively on animals Vs. the 6 months it took to make COVID-19 vaccines which then skipped animal trials and were tested directly on humans en masse…YES you volunteered to be a guinea-pig, and NO it did nothing to prevent COVID-19 infection or spread, and YES you are very likely to suffer negative health effects as a result of your decision to inject an experimental, synthetic, foreign drug into your body.
You must ask yourself…when the survival rate for COVID-19 in healthy individuals under 60 is around 99.85% globally…why would you risk taking an experimental mRNA drug injection, with no data on it’s long-term safety, which now has recorded tens of thousands of severe adverse events on official databases such as VAERS, Vigibase and the UK Yellowcard system? And why in gods name would you inject that dangerous drug in your children?
On a separate note…I’m still rather confused as to why people are getting health advice from Bill Gates; his OS is riddled with problems and was originally compiled mostly of stolen code from other developers…the man has absolutely no business advising people to take vaccines.